Genotoxicity of Euphorbia hirta: An Allium cepa Assay

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Genotoxicity of Euphorbia hirta: an Allium cepa assay.

The potential genotoxic effects of methanolic extracts of Euphorbia hirta which is commonly used in traditional medicine to treat a variety of diseased conditions including asthma, coughs, diarrhea and dysentery was investigated using Allium cepa assay. The extracts of 125, 250, 500 and 1,000 µg/mL were tested on root meristems of A. cepa. Ethylmethanesulfonate was used as positive control and ...

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Bioindicator of Genotoxicity: The Allium cepa Test

Solange Bosio Tedesco1,2 and Haywood Dail Laughinghouse IV3,4 1Graduate Program in Agrobiology, Department of Biology Universidade Federal de Santa Maria (UFSM), Santa Maria 2Graduate Program in Agronomy, UFSM, Santa Maria 3National Museum of Natural History, Smithsonian Institution, Washington, DC 4College of Computer, Mathematical & Natural Sciences University of Maryland, College Park, MD 1,...

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Allium cepa Root Chromosomal Aberration Assay: An Efficient Test System for Evaluating Genotoxicity of Agricultural Soil

Agricultural soils are increasingly becoming sinks for wide number of hazardous contaminants which ultimately result in pollution. Plant bioassays, because of their sensitivity and affordability, have been recommended as first-tier assays which enable the detection of contaminants. The present study involves genotoxicity of four soil samples collected from different regions of Amritsar employin...

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Cytotoxicity and genotoxicity assessment of Euphorbia hirta in MCF-7 cell line model using comet assay.

OBJECTIVE To evaluate the cytotoxicity and genotoxicity activity of Euphorbia hirta (E. hirta) in MCF-7 cell line model using comet assay. METHODS The cytotoxicity of E. hirta extract was investigated by employing brine shrimp lethality assay and the genotoxicity of E. hirta was assessed by using Comet assay. RESULTS Both toxicity tests exhibited significant toxicity result. In the comet as...

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Allium Cepa Root Chromosomal Aberration Assay: A Review

Higher plants, an important material for genetic tests to monitor various pollutant present in the environment. Among the plant species, Alium cepa has been used to evaluate chromosome aberrations and disturbances in the mitotic cycle. Now days, it has been used to assess a great number of genotoxic/antigenotoxic agents, which contributes to its increasing application in environmental monitorin...

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ژورنال

عنوان ژورنال: Molecules

سال: 2012

ISSN: 1420-3049

DOI: 10.3390/molecules17077782